Prof. Sina Bartfeld heads the department of Medical Biotechnology at the Technical University Berlin and leads a group at the University of Würzburg. The Bartfeld lab is interested in the molecular basis of epithelial diseases, especially host cell responses to infections of the gastrointestinal tract. While asking basic mechanistic questions in infection, innate immune signaling and cancer biology, we always strive to develop and improve in vitro models. We almost exclusively work with adult stem cell-derived organoids as model for human physiology and pathology.