São Paulo School of Advanced Science on Stem Cell Biology 2023

Maria Carolina (Carol) Marchetto is an Assistant Professor at the Anthropology Department, UC San Diego, and serves on the CARTA Internal Advisory Board. Dr. Marchetto earned a BSc in Biological Sciences in 1998 and a Ph.D. in Microbiology in 2005 from the University of Sao Paulo, Brazil. Dr. Marchetto moved to San Diego in 2005 for her postdoctoral research in stem cells and neuroscience in the lab of Dr. Fred Gage at the Salk Institute. Prior to her appointment at UC San Diego, Dr. Marchetto was a Staff Scientist at the Laboratory of Genetics at The Salk Institute where she led projects that studied neuronal development using human and nonhuman primate stem cells. Her current work focuses on using patient-derived induced pluripotent stem cells to study the cellular behavior of human neurons in neuropsychiatric and neurodevelopmental conditions such as Autism and Bipolar Disorder. Dr. Marchetto’s work is also focused on human evolution in the context of human brain expansion and neuronal development. Her innovative approach uses stem cell models from human and nonhuman primate species to test hypotheses about the role of disruptions to human-specific cellular and molecular signatures in development and their potential impact on mental health. She is a BRAINS Program Fellow, and her work has received funding from the National Institutes of Mental Health and the Larry L. Hillblom Foundation.